The use of samarium diiodide in organic and polymer synthesis and properties of samarium diiodide are examined and the results of its employment for the synthesis of a wide variety of compounds nbsp samarium(ii) iodide – wikipedia (ii) iodide is a reagent for carbon-carbon bond formation, the book quotorganic synthesis using samarium . Samarium diiodide is one of the most important reducing agents available to synthetic organic chemists the lanthanide(ii) reagent acts by single-electron transfer to organic substrates leading to the formation of both radical and/or anionic inter. Samarium(ii) iodide mediated cyclizations in natural product synthesis -samarium diiodide was first reported by kagan in 1977 -samarium diiodide . Samarium (ii) diiodide (smi 2) is a powerful one-electron reducing agent that has found widespread use in organic synthesis 2 one of the widely applied processes involving the use of smi 2 includes the intramolecular ketyl olefin radical coupling reaction to achieve carbon–carbon bond formation between aldehydes or ketones and olefins 3 recently, cyclization reactions involving the use of .
Samarium(ii) iodide is an inorganic compound with the formula smi 2when employed as a solution for organic synthesis, it is known as kagan's reagent smi 2 is a green solid and its solutions are green as well. Contents abbrevations xiv chapter 1 introduction 11 organic synthesis using samariumdiiodide: apractical guide 111 aimsofthe book 112 further reading 12 introducingthe reagent 121 working with sml2. Conjugate addition reactions in organic synthesis in tetrahedron organic samarium diiodide rapidly reduces pyridine to piperidine in the presence of water at .
Samarium diiodide as coupling agent between aldehydes and organic halides for the synthesis of homoallylic and homobenzylic alcohols. Samarium diiodide has been extensively applied to organic synthesis' it has cleavage of diorganyl disulfides or sodium alkylthiolates with samarium diiodide. New progress in the application of samarium reagent to organic synthesis: liu yong-jun, zhang yong-min (department of chemistry, zhejiang university, hangzhou 310028). Search results for samarium diiodide at sigma-aldrich. 1 samarium(ii)-mediated reactions in organic synthesis - method development and mechanistic investigation tobias ankner department of chemistry.
Samarium diiodide mediated barbier-type reaction of 2-chloromethylbenzoxazole and 2-chloromethylbenzothiazole with carbonyl compounds: a convenient synthesis of 1-(β-hydroxyalkyl)benzoxazoles and 1-(β-hydroxyalkyl)benzothiazoles. Samarium(ii) iodide in organic synthesis (pdf, macmillan’s group) some synthetic applications of samarium (ii) iodide (pdf) samarium diiodide: discovery and applications (pdf, dong group). A novel method for indole skeleton synthesis under mild conditions mediated by samarium(ii) diiodide has been developed the reaction of n-allenyl-2-iodoaniline derivatives with smi2 in the presence of hmpa and i-proh at 0 °c afforded indole derivatives in high yields. Stanford libraries' official online search tool for books, media, journals, databases, government documents and more.
Get this from a library organic synthesis using samarium diiodide a practical guide [david j procter robert a flowers, ii troels skrydstrup] -- a concise practical approach to the chemistry of the versatile lanthanide reagent samarium diiodide, containing illustrative practical procedures and literature references, samarium diiodide is one . Preparation and use of samarium diiodide (smi2) in organic synthesis: the mechanistic role of hmpa and ni(ii) salts in the samarium barbier reaction. Samarium diiodide (smi2) is a one-electron reducing agent that is employed extensively in organic synthesis to bring about a wide variety of transformations. Organic synthesis using samarium diiodide research output: chapter in book/report/conference proceeding chapter. Samarium diiodide (smi 2) is a one-electron reducing agent that is employed extensively in organic synthesis to bring about a wide variety of transformations its ability to mediate both radical and anionic processes as well as cascade reactions involving both types of reactivity is central to its status as one of the most versatile reducing .
12 jin wang, fabien gasc, jacques prandi, samarium diiodide mediated coupling of 2-pyridylsulfonyl furanosides with aldehydes and ketones: a general synthesis ofc-furanosides, european journal of organic chemistry, 2015, 2015, 12, 2691wiley online library. Samarium metal in organic synthesis banik, bimal k 2002-08-01 00:00:00 recently organolanthanides have been widely employed as useful reagents in organic synthesis since the pioneering studies by kagan and his co‐workers demonstrated the effectiveness of samarium diiodide as a strong one‐electron transfer reducing agent, the utility of . The methods of synthesis and properties of samarium diiodide are examined and the results of its employment for the synthesis of a wide variety of compounds are surveyed. Introduced by henri kagan more than three decades ago, samarium diiodide (smi 2) has found increasing application in chemical synthesis this single-electron reducing agent has been particularly useful in c c bond formations, including those found in total synthesis endeavors.
Diverse reactions with samarium metal in the presence of different additives are studied synthesis of diverse organic compounds some of the resulting . A highly stereoselective synthesis of aromatic α,β-unsaturated amides was achieved by treatment of aromatic α,β-epoxyamides with samarium diiodide α,β-epoxyamides are easily prepared by the reaction of enolates derived from α-chloroamides with carbonyl compounds at -78°c.